Among the topics Saturday Night Live‘s Weekend Update took on were Health and Human Services Secretary Robert F. Kennedy Jr.’s latest unscientific comments and Homeland Security Secretary Kristi Noem‘s odd attempt to blame Democrats for the government shutdown.
“Health secretary RFK Jr., seen here trying to cure cancer with his mind, said this week that men who were circumcised are more likely to be autistic,” co-anchor Colin Jost said of the proponent of vaccine misinformation, who has claimed that Tylenol is linked to autism. “—Which isn’t surprising coming from a man who looks like he’s made out of foreskin.”
Jost then addressed how Noem is subjecting airline passengers in line at Transportation Security Administration checkpoints to a video of her insisting that the government shutdown, which is occurring under a GOP-controlled Senate, House and a Republican president, is actually all Democrats’ fault.
Weekend Update with Colin Jost and Michael Che! pic.twitter.com/sGuxKnjsei
— Saturday Night Live – SNL (@nbcsnl) October 12, 2025
Jost then played a portion of the video—which turned out to be the first line of fictional serial killer Jigsaw’s videotaped message to his tortured victims: “I want to play a game.”
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Weekend Update also addressed a recent development—of questionable legality—in the U.S. Treasury.
That department, Michael Che announced, “is planning to release a silver dollar with President Trump’s face on it. And then on the other side, he has Harriet Tubman in a head lock.”
Tubman, the abolitionist and slave rescuer, would replace Andrew Jackson on the $20, Treasury Secretary Jack Lew said way back in 2016. But it’s looking like that may not come about until at least 2030.
Jost also called out Trump for proclaiming an end to Indigenous People’s Day and labeling Christopher Columbus “original American hero.”
“So while Trump is rounding up people with ICE, he is praising Columbus, a guy who literally brought boat loads of Hispanics to America,” Jost said.
Weekend Update concluded with a joke off between Jost, Che, and former anchors Tina Fey, Seth Meyers and Amy Poehler, who was SNL‘s host Saturday.
Weekend Update Joke Off with Amy, Tina, and Seth! pic.twitter.com/Q1hTAwaEnP
— Saturday Night Live – SNL (@nbcsnl) October 12, 2025
From Rolling Stone US